placeholder image

The BioAge platform identifies key molecular mechanisms of healthy human longevity and reveals new drug targets for diseases of aging

Our platform

65M+ data points across 10K+ patients over 45+ years of human aging

sphere
SOURCE

Analyze longitudinal samples connected to health records, representing decades of human aging

CHARACTERIZE

Measure 10K+ molecules per sample using cutting-edge multi-omics

MAP

Leverage AI to map longevity pathways and identify drug targets

VALIDATE

Validate targets & assets in naturally aged animal models

BUILD

Develop novel molecules through in-licensing or internal discovery

TRIAL

Perform efficient trials in acute diseases

scheme
map

Unprecedented visibility into human aging

BioAge’s diverse human aging cohorts contain patients’ longitudinal samples, data, and health records for up to 45 years.

axis
1.5M+ clinical data points
10K+ unique patients
up to 45+ years of longitudinal samples and health records
up to 95% complete lifespan capture
circle

Why we start with human data

translational-icon
Identify
translational aspects of known aging biology
biomarkers-icon
Identify
predictive aging biomarkers
novel-icon
Discover
highly novel biology of human aging

Our cohorts

begin with healthy middle-aged patients, allowing us to track aging outcomes and identify what drives them

Our platform helps us understand who lives long, who lives well, and why
axis

Why we use longitudinal data

decline-icon
Identify the molecular signatures of early functional decline that leads to severe disease
physiology-icon
Discover key alterations in molecular pathways that occur over decades and drive differences in elderly physiology
aging-icon
Discover novel mechanistic drivers of the fundamental aging process that underpins severe disease

Our data first, mechanism-agnostic approach

Mechanism-agnostic approach enables us to identify drugs targets at the intersection of known and novel aging biology

axis

From human discovery in silico to focused mechanistic validation in vivo

Targets and assets revealed by our discovery platform are rigorously validated in naturally aged rodent models of disease. To ensure human relevance, we focus on aspects of aging that unfold in similar ways in mice and humans.

bioage-model
Left gradient Right gradient