Pipeline

We are harnessing the biology of human aging to develop new therapies for metabolic diseases

We are harnessing the biology of human aging to develop new therapies for metabolic diseases

Program
Mechanism of Action
Target dosing
Indication
Status
BGE - 102
NLRP3
(CNS penetrant)
NLRP3 inhibitor
(CNS penetrant)
Oral QD
Obesity
IND-enabling pointer
Discoverу Lead Op IND-enabling Ph 1 Ph 2 Ph 3
Lead Op pointer
Discoverу Lead Op IND-enabling Ph 1 Ph 2 Ph 3
APJ
Oral
APJ
Parenteral
APJ agonist
Oral QD SQ QW
Obesity
Lead Op pointer
Discoverу Lead Op IND-enabling Ph 1 Ph 2 Ph 3
Lead Op pointer
Discoverу Lead Op IND-enabling Ph 1 Ph 2 Ph 3
Program 1
Program 2
Target discovery
Undisclosed Undisclosed Multiple targets
- - -
Cardiometabolic (various) Cardiometabolic (various) -
Disc. pointer
Discoverу Lead Op IND-enabling Ph 1 Ph 2 Ph 3
Disc. pointer
Discoverу Lead Op IND-enabling Ph 1 Ph 2 Ph 3
Disc. pointer
Discoverу Lead Op IND-enabling Ph 1 Ph 2 Ph 3
Program
BGE - 102
NLRP3 (CNS penetrant)
Mechanism of Action NLRP3 inhibitor
(CNS penetrant)
Target dosing Oral QD
Indication Obesity
Status
IND-enabling pointer
Discoverу Lead Op IND-enabling Ph 1 Ph 2 Ph 3
Mechanism of Action NLRP3 inhibitor
(CNS penetrant)
Target dosing Oral QD
Indication Obesity
Status
Lead Op pointer
Discoverу Lead Op IND-enabling Ph 1 Ph 2 Ph 3
View more
Program
APJ Oral
APJ Parenteral
Mechanism of Action APJ agonist
Target dosing Oral QD
Indication Obesity
Status
Lead Op pointer
Discoverу Lead Op IND-enabling Ph 1 Ph 2 Ph 3
Mechanism of Action APJ agonist
Target dosing SQ QW
Indication Obesity
Status
Lead Op pointer
Discoverу Lead Op IND-enabling Ph 1 Ph 2 Ph 3
View more
Program
Program 1
Program 2
Target discovery
Mechanism of Action Undisclosed
Target dosing -
Indication Cardiometabolic (various)
Status
Disc. pointer
Discoverу Lead Op IND-enabling Ph 1 Ph 2 Ph 3
Mechanism of Action Undisclosed
Target dosing -
Indication Cardiometabolic (various)
Status
Disc. pointer
Discoverу Lead Op IND-enabling Ph 1 Ph 2 Ph 3
Mechanism of Action Multiple targets
Target dosing -
Indication -
Status
Disc. pointer
Discoverу Lead Op IND-enabling Ph 1 Ph 2 Ph 3
Left gradient Right gradient