Pipeline
We are harnessing the biology of human aging to develop new therapies for cardiometabolic diseases
We are harnessing the biology of human aging to develop new therapies for cardiometabolic diseases
Program
Mechanism of Action
Target dosing
Indication
Status
BGE-102
NLRP3 inhibitor
(CNS penetrant)
(CNS penetrant)
Oral QD
Chronic inflammation
Diabetic macular edema
Ph 2
Discovery
Lead Op
IND-enabling
Ph 1
Ph 2
Ph 3
Ph 2
Discovery
Lead Op
IND-enabling
Ph 1
Ph 2
Ph 3
APJ
Oral
Oral
APJ
Parenteral
Parenteral
APJ agonist
Oral QD
SQ QW
Obesity
Lead Op
Discovery
Lead Op
IND-enabling
Ph 1
Ph 2
Ph 3
Lead Op
Discovery
Lead Op
IND-enabling
Ph 1
Ph 2
Ph 3
Program 1
Program 2
Target discovery
Undisclosed
Undisclosed
Multiple targets
-
-
-
Cardiometabolic (various)
Cardiometabolic (various)
-
Disc.
Discovery
Lead Op
IND-enabling
Ph 1
Ph 2
Ph 3
Disc.
Discovery
Lead Op
IND-enabling
Ph 1
Ph 2
Ph 3
Disc.
Discovery
Lead Op
IND-enabling
Ph 1
Ph 2
Ph 3
Program
BGE-102
BGE-102
Mechanism of Action
NLRP3 inhibitor
(CNS penetrant)
(CNS penetrant)
Target dosing
Oral QD
Indication
Chronic inflammation
Status
![]()
Ph 2
Discovery
Lead Op
IND-enabling
Ph 1
Ph 2
Ph 3
Mechanism of Action
NLRP3 inhibitor
(CNS penetrant)
(CNS penetrant)
Target dosing
Oral QD
Indication
Diabetic macular edema
Status
![]()
Ph 2
Discovery
Lead Op
IND-enabling
Ph 1
Ph 2
Ph 3
Program
APJ
Oral
APJ
Parenteral
Mechanism of Action
APJ agonist
Target dosing
Oral QD
Indication
Obesity
Status
Lead Op
Discovery
Lead Op
IND-enabling
Ph 1
Ph 2
Ph 3
Mechanism of Action
APJ agonist
Target dosing
SQ QW
Indication
Obesity
Status
Lead Op
Discovery
Lead Op
IND-enabling
Ph 1
Ph 2
Ph 3
Program
Program 1
Program 2
Target discovery
Mechanism of Action
Undisclosed
Target dosing
-
Indication
Cardiometabolic (various)
Status
![]()
Disc.
Discovery
Lead Op
IND-enabling
Ph 1
Ph 2
Ph 3
Mechanism of Action
Undisclosed
Target dosing
-
Indication
Cardiometabolic (various)
Status
![]()
Disc.
Discovery
Lead Op
IND-enabling
Ph 1
Ph 2
Ph 3
Mechanism of Action
Multiple targets
Target dosing
-
Indication
-
Status
![]()
Disc.
Discovery
Lead Op
IND-enabling
Ph 1
Ph 2
Ph 3
